YL201
Drug Detail
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| Drug Name | YL201 |
| Trade Name | |
| Synonyms | YL-201|YL 201 |
| Drug Descriptions |
YL201 is an antibody-drug conjugate (ADC) comprising an antibody targeting CD276 (B7-H3) linked to a topoisomerase I inhibitor, which potentially induces apoptosis in tumor cells expressing CD276 (B7-H3) (Ann Oncol 35 (2024): S485, NCI Drug Dictionary). |
| DrugClasses | CD276 Antibody 21 |
| CAS Registry Number | NA |
| NCIT ID | C188794 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + Tarlatamab + YL201 | Atezolizumab Tarlatamab YL201 | 0 | 1 |
| Atezolizumab + YL201 | Atezolizumab YL201 | 0 | 1 |
| Durvalumab + Tarlatamab + YL201 | Durvalumab Tarlatamab YL201 | 0 | 1 |
| Tarlatamab + YL201 | Tarlatamab YL201 | 0 | 1 |
| YL201 | YL201 | 0 | 1 |
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