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| Drug Name | Tarlatamab |
| Trade Name | Imdelltra |
| Synonyms | AMG 757|AMG757|AMG-757|tarlatamab-dlle |
| Drug Descriptions |
Imdelltra (tarlatamab) is a bispecific antibody that targets CD3 on T-cells and delta-like protein 3 (DLL3) expressed by tumor cells, which may lead to cytotoxic killing of Dll3-expressing tumor cells (PMID: 31215500). Imdelltra (tarlatamab) is FDA-approved for use in patients with extensive stage small cell lung cancer who progressed on or after platinum-based chemotherapy (FDA.gov). |
| DrugClasses | CD3 Antibody 119 DLL3 Antibody 10 |
| CAS Registry Number | 2307488-83-9 |
| NCIT ID | C147027 |