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| Drug Name | TNG908 |
| Trade Name | |
| Synonyms | TNG-908|TNG 908 |
| Drug Descriptions |
TNG908 is an MTAP-null selective PRMT5 inhibitor, which potentially decreases proliferation of tumor cells harboring MTAP deletion and inhibits tumor growth (PMID: 39756156). |
| DrugClasses | PRMT5 Inhibitor 21 |
| CAS Registry Number | NA |
| NCIT ID | C187119 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abemaciclib + TNG908 | Abemaciclib TNG908 | 0 | 0 |
| AG-270 + TNG908 | AG-270 TNG908 | 0 | 0 |
| IDE397 + TNG908 | IDE397 TNG908 | 0 | 0 |
| Palbociclib + TNG908 | Palbociclib TNG908 | 0 | 0 |
| TNG908 | TNG908 | 0 | 1 |