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Drug Name | Palbociclib |
Trade Name | Ibrance |
Synonyms | PD0332991|PD-0332991 |
Drug Descriptions |
Ibrance (palbociclib) is a selective inhibitor of cyclin-dependent kinase 4 (CDK4) and 6 (CDK6) (PMID: 19874578). Ibrance (palbociclib) is approved in combination with an aromatase inhibitor in postmenopausal patients with ER-positive, ERBB2 (HER2)-negative metastatic breast cancer, and in combination with Faslodex (fulvestrant) in patients with ER-positive, ERBB2 (HER2)-negative metastatic breast cancer (FDA.gov). |
DrugClasses | CDK4/6 Inhibitor 14 |
CAS Registry Number | 571190-30-2 |
NCIT ID | C49176 |