DB-1305
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| Drug Name | DB-1305 |
| Trade Name | |
| Synonyms | DB1305|DB 1305|BNT325|BNT 325|BNT-325 |
| Drug Descriptions |
DB-1305 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting TROP2 conjugated to a DNA topoisomerase I inhibitor, which potentially results in antitumor activity (Ann Oncol 34 (2023): S480). |
| DrugClasses | TROP2 Antibody 18 |
| CAS Registry Number | NA |
| NCIT ID | C188363 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BNT327 + DB-1305 | BNT327 DB-1305 | 0 | 1 |
| DB-1305 | DB-1305 | 0 | 1 |
| DB-1305 + DB-1311 | DB-1305 DB-1311 | 0 | 1 |
| DB-1305 + Pembrolizumab | DB-1305 Pembrolizumab | 0 | 1 |
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