SAR443579
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| Drug Name | SAR443579 |
| Trade Name | |
| Synonyms | SAR-443579|SAR 443579|IPH 6101|IPH-6101|IPH6101|bexatamig |
| Drug Descriptions |
SAR443579 is a trispecific natural killer (NK) cell engager (NKCE) targeting tumor-expressed CD123 (IL3RA), and the NK-cell specific receptors NKp46 and CD16, potentially leading to NK cell-mediated killing of tumor cells expressing CD123 (IL3RA) (J Clin Oncol 41, 2023 (suppl 16; abstr 7005)). |
| DrugClasses | CD123 (IL3RA) Antibody 14 |
| CAS Registry Number | NA |
| NCIT ID | C185407 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Azacitidine + SAR443579 + Venetoclax | Azacitidine SAR443579 Venetoclax | 0 | 1 |
| SAR443579 | SAR443579 | 0 | 1 |
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