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Drug Name | SAR443579 |
Trade Name | |
Synonyms | SAR-443579|SAR 443579|IPH 6101|IPH-6101|IPH6101 |
Drug Descriptions |
SAR443579 is a trispecific natural killer (NK) cell engager (NKCE) comprised of antibodies targeting tumor-expressed CD123, and the NK-cell specific receptors NKp46 and CD16, potentially leading to NK cell-mediated killing of tumor cells expressing CD123 (J Clin Oncol 41, 2023 (suppl 16; abstr 7005)). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C185407 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Azacitidine + SAR443579 + Venetoclax | Azacitidine SAR443579 Venetoclax | 0 | 1 |
SAR443579 | SAR443579 | 0 | 1 |