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Drug Name | YH004 |
Trade Name | |
Synonyms | YH 004|YH-004 |
Drug Descriptions |
YH004 is an agonistic monoclonal antibody that targets CD137 (4-1BB; TNFRSF9), resulting in increased CD137 signaling and potentially leading to inhibition of T-regulatory cells and induction of a cytotoxic T-lymphocyte (CTL)- and NK cell-mediated antitumor response, resulting in tumor cell killing (NCI Drug Dictionary). |
DrugClasses | TNFRSF9 Antibody 32 |
CAS Registry Number | NA |
NCIT ID | C184376 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
YH004 | YH004 | 0 | 1 |