YH004
Drug Detail
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| Drug Name | YH004 |
| Trade Name | |
| Synonyms | YH 004|YH-004 |
| Drug Descriptions |
YH004 is an agonistic monoclonal antibody that targets CD137 (4-1BB; TNFRSF9), resulting in increased CD137 signaling and potentially leading to inhibition of T-regulatory cells and induction of a cytotoxic T-lymphocyte (CTL)- and NK cell-mediated antitumor response, resulting in tumor cell killing (NCI Drug Dictionary). |
| DrugClasses | TNFRSF9 Antibody 36 |
| CAS Registry Number | NA |
| NCIT ID | C184376 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| YH004 | YH004 | 0 | 1 |
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