ABL503
Drug Detail
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| Drug Name | ABL503 |
| Trade Name | |
| Synonyms | ABL-503|ABL 503|TJ-L14B|ragistomig |
| Drug Descriptions |
ABL503 is a bispecific antibody that targets both CD274 (PD-L1) and TNFRSF9 (4-1BB), leading to activation of TNFRSF9 (4-1BB) and decreased CD274 (PD-L1) signaling, potentially resulting in activation of an antitumor immune response and inhibition of tumor growth (PMID: 34230109). |
| DrugClasses | PD-L1/PD-1 antibody 133 TNFRSF9 Antibody 36 |
| CAS Registry Number | NA |
| NCIT ID | C179637 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ABL503 | ABL503 | 0 | 1 |
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