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Drug Name | BAFFR-CAR T cells |
Trade Name | |
Synonyms | Autologous BAFFR-CAR-expressing T-cells |
Drug Descriptions |
BAFFR-CAR T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets B-cell activating factor receptor (BAFF-R) and containing TNFRSF9 (4-1BB) and CD3zeta signaling domains, which potentially result in cytotoxic effects against tumor cells (PMID: 31554741). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C178272 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BAFFR-CAR T cells | BAFFR-CAR T cells | 0 | 3 |