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Therapy Name | BAFFR-CAR T cells |
Synonyms | |
Therapy Description |
BAFFR-CAR T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets B-cell activating factor receptor (BAFF-R) and containing TNFRSF9 (4-1BB) and CD3zeta signaling domains, which potentially result in cytotoxic effects against tumor cells (PMID: 31554741). |