Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | Dapansutrile |
| Trade Name | |
| Synonyms | OLT1177|OLT 1177|OLT-1177 |
| Drug Descriptions |
Dapansutrile inhibits NLRP3 by blocking ATPase activity, which potentially reduces myeloid-derived suppressor cell expansion and tumor growth (PMID: 33649199). |
| DrugClasses | |
| CAS Registry Number | 54863-37-5 |
| NCIT ID | C166608 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Dapansutrile | Dapansutrile | 0 | 0 |
| Dapansutrile + Pembrolizumab | Dapansutrile Pembrolizumab | 0 | 1 |
| Dapansutrile + unspecified PD-L1 antibody | Dapansutrile unspecified PD-L1 antibody | 0 | 0 |