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Drug Name | Dapansutrile |
Trade Name | |
Synonyms | OLT1177|OLT 1177|OLT-1177 |
Drug Descriptions |
Dapansutrile inhibits NLRP3 by blocking ATPase activity, which potentially reduces myeloid-derived suppressor cell expansion and tumor growth (PMID: 33649199). |
DrugClasses | |
CAS Registry Number | 54863-37-5 |
NCIT ID | C166608 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Dapansutrile | Dapansutrile | 0 | 0 |
Dapansutrile + Pembrolizumab | Dapansutrile Pembrolizumab | 0 | 1 |
Dapansutrile + unspecified PD-L1 antibody | Dapansutrile unspecified PD-L1 antibody | 0 | 0 |