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Drug Name | LMY-920 |
Trade Name | |
Synonyms | LMY920|LMY 920|Autologous BAFF-expressing CAR T Cells |
Drug Descriptions |
LMY-920 comprises autologous CD4- and CD8-positive T-lymphocytes engineered to express a chimeric antigen receptor (CAR) containing the B-cell activating factor (BAFF) ligand, which potentially induce cytotoxicity against tumor cells expressing BAFF-R (TNFRSF13C), BCMA (TNFRSF17), or TACI (TNFRSF13B) (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C187330 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
LMY-920 | LMY-920 | 0 | 2 |