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Drug Name | BBP-398 |
Trade Name | |
Synonyms | BBP 398|BBP398|IACS-15509|IACS 15509|IACS15509|BMS-986466|BMS986466 |
Drug Descriptions |
BBP-398 is a small molecule SHP2 inhibitor that blocks ERK signaling and potentially reduces tumor cell viability and tumor growth (Mol Cancer Ther 2021;20(12 Suppl):Abstract nr P207). |
DrugClasses | SHP2 Inhibitor 20 |
CAS Registry Number | NA |
NCIT ID | C177417 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Adagrasib + BBP-398 | Adagrasib BBP-398 | 0 | 1 |
Adagrasib + BBP-398 + Cetuximab | Adagrasib BBP-398 Cetuximab | 0 | 1 |
BBP-398 | BBP-398 | 0 | 1 |
BBP-398 + Nivolumab | BBP-398 Nivolumab | 0 | 1 |
BBP-398 + Sotorasib | BBP-398 Sotorasib | 0 | 1 |