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Drug Name TU2218
Trade Name
Synonyms TU-2218|TU 2218|NCE 401|NCE401|NCE-401
Drug Descriptions

TU2218 inhibits VEGFR2 and TGFBR1 (ALK5), which potentially results in enhanced antitumor immune response (Cancer Res 2022;82(12_Suppl):Abstract nr 5538).

DrugClasses TGFBR1 inhibitor 16 VEGFR2 Inhibitor 37
CAS Registry Number NA
NCIT ID C186379

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + TU2218 Pembrolizumab TU2218 0 1
TU2218 TU2218 0 1
TU2218 + unspecified PD-1 antibody TU2218 unspecified PD-1 antibody 0 1


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