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| Drug Name | AOH1996 |
| Trade Name | |
| Synonyms | AOH 1996|AOH-1996 |
| Drug Descriptions |
AOH1996 targets PCNA and increases interaction with POLR2A, resulting in increased POLR2A degradation, and potentially leading to decreased DNA repair, increased replication stress and tumor cell apoptosis, and reduced tumor growth (PMID: 37531956). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C185144 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AOH1996 | AOH1996 | 0 | 2 |
| AOH1996 + Azacitidine + Venetoclax | AOH1996 Azacitidine Venetoclax | 0 | 1 |
| AOH1996 + Venetoclax | AOH1996 Venetoclax | 0 | 1 |
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