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Drug Name | GEN-1 |
Trade Name | |
Synonyms | phIL-12-005|GEN1|GEN 1 |
Drug Descriptions |
GEN-1 comprises a plasmid engineered to express IL-12 encapsulated within a lipopolymer, which potentially results in increased antitumor immune response (PMID: 28802766, PMID: 34326131). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C49178 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + Carboplatin + GEN-1 + Paclitaxel | Bevacizumab Carboplatin GEN-1 Paclitaxel | 0 | 1 |
Carboplatin + GEN-1 + Paclitaxel | Carboplatin GEN-1 Paclitaxel | 0 | 0 |
GEN-1 | GEN-1 | 0 | 0 |
GEN-1 + Pegylated liposomal doxorubicin | GEN-1 Pegylated liposomal doxorubicin | 0 | 0 |