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| Drug Name | GEN-1 |
| Trade Name | |
| Synonyms | phIL-12-005|GEN1|GEN 1|IMNN-001|IMNN 001|IMNN001 |
| Drug Descriptions |
GEN-1 comprises a plasmid engineered to express IL-12 encapsulated within a lipopolymer, which potentially results in increased antitumor immune response (PMID: 28802766, PMID: 34326131). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C49178 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bevacizumab + Carboplatin + GEN-1 + Paclitaxel | Bevacizumab Carboplatin GEN-1 Paclitaxel | 0 | 1 |
| Carboplatin + GEN-1 + Niraparib + Paclitaxel | Carboplatin GEN-1 Niraparib Paclitaxel | 0 | 1 |
| Carboplatin + GEN-1 + Olaparib + Paclitaxel | Carboplatin GEN-1 Olaparib Paclitaxel | 0 | 1 |
| Carboplatin + GEN-1 + Paclitaxel | Carboplatin GEN-1 Paclitaxel | 0 | 0 |
| GEN-1 | GEN-1 | 0 | 0 |
| GEN-1 + Pegylated liposomal doxorubicin | GEN-1 Pegylated liposomal doxorubicin | 0 | 0 |