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Drug Name | Pegylated liposomal doxorubicin |
Trade Name | Doxil |
Synonyms | ATI-0918|CAELYX|liposomal doxorubicin |
Drug Descriptions |
Doxil (pegylated liposomal doxorubicin) comprises the anthracyline doxorubicin, which intercalates into DNA and disrupts DNA replication, encapsulated in a liposome, which improves tumor penetration and decreases toxicity (NCI Drug Dictionary), and is FDA approved for ovarian cancer, AIDS-related Kaposi's sarcoma, and multiple myeloma (FDA.gov). |
DrugClasses | Chemotherapy - Anthracycline 13 |
CAS Registry Number | NA |
NCIT ID | C1555 |