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| Drug Name | AB-1015 |
| Trade Name | |
| Synonyms | AB 1015|AB1015 |
| Drug Descriptions |
AB-1015 is an integrated circuit T (ICT) cell therapy that comprises T cells engineered to express a priming receptor that binds to ALPG/P and induces expression of a chimeric antigen receptor (CAR) that targets mesothelin (MSLN), as well as shRNA that targets FAS and PTPN2, potentially resulting in increased killing of ALPG/P and MSLN-expressing tumor cells (Cancer Res (2022) 82 (12_Supplement): 585). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C190955 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AB-1015 | AB-1015 | 0 | 1 |
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