CART-ddBCMA
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| Drug Name | CART-ddBCMA |
| Trade Name | |
| Synonyms | Anitocabtagene autoleucel |
| Drug Descriptions |
CART-ddBCMA are autologous T-lymphocytes that have been engineered to express a chimeric antigen receptor (CAR) with a synthetic antigen-binding domain targeting BCMA (TNFRSF17) and containing CD137 (4-1BB) and CD3 zeta signaling domains, which potentially have antitumor activity (PMID: 35468618). |
| DrugClasses | TNFRSF17 Immune Cell Therapy 27 |
| CAS Registry Number | NA |
| NCIT ID | C199003 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ACLX-001 + CART-ddBCMA | ACLX-001 CART-ddBCMA | 0 | 0 |
| CART-ddBCMA | CART-ddBCMA | 0 | 4 |
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