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Drug Name | CART-ddBCMA |
Trade Name | |
Synonyms | Anitocabtagene autoleucel |
Drug Descriptions |
CART-ddBCMA are autologous T-lymphocytes that have been engineered to express a chimeric antigen receptor (CAR) with a synthetic antigen-binding domain targeting BCMA (TNFRSF17) and containing CD137 (4-1BB) and CD3 zeta signaling domains, which potentially have antitumor activity (PMID: 35468618). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C199003 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ACLX-001 + CART-ddBCMA | ACLX-001 CART-ddBCMA | 0 | 0 |
CART-ddBCMA | CART-ddBCMA | 0 | 3 |