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Drug Name | EBC-129 |
Trade Name | |
Synonyms | EBC129|EBC 129 |
Drug Descriptions |
EBC-129 is an antibody-drug conjugate (ADC) comprising an antibody targeting N-glycosylated CEACAM5/6 linked to monomethyl auristatin E (MMAE), which potentially induces antitumor activity (Ann Oncol 35 (2024): S516). |
DrugClasses | CEACAM5 Antibody 8 CEACAM6 Antibody 3 |
CAS Registry Number | NA |
NCIT ID | C200045 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
EBC-129 | EBC-129 | 0 | 1 |
EBC-129 + Pembrolizumab | EBC-129 Pembrolizumab | 0 | 1 |