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| Drug Name | IOS-1002 |
| Trade Name | |
| Synonyms | IOS 1002|IOS1002 |
| Drug Descriptions |
IOS-1002 is fusion protein comprising a modified version of HLA-B57 fused to IgG4 Fc, which targets the LILRB1 (ILT2), LILRB2 (ILT4), and KIR3DL1 receptors on immune cells and potentially increases antitumor immune response (PMID: 39199672). |
| DrugClasses | LILRB2 Antibody 12 |
| CAS Registry Number | NA |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| IOS-1002 | IOS-1002 | 0 | 1 |
| IOS-1002 + unspecified PD-1 antibody | IOS-1002 unspecified PD-1 antibody | 0 | 1 |