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| Drug Name | NT-175 |
| Trade Name | |
| Synonyms | NT175|NT 175 |
| Drug Descriptions |
NT-175 comprises autologous T-lymphocytes engineered to express an HLA-A*02:01-restricted T-cell receptor (TCR) targeting TP53 R175H, and to lack expression of TGFBR2, which potentially induces a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing TP53 R175H and inhibits tumor growth (J Clin Oncol 2024 42:16_suppl, 5011, NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C200071 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| NT-175 | NT-175 | 0 | 1 |
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