CART123 cells
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| Drug Name | CART123 cells |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
CART123 cells are T-cells engineered to express a chimeric antigenic receptor (CAR) targeting CD123 and linked to 4-1BB and CD3zeta signaling domains, which potentially enhance antitumor immune response and inhibit tumor growth (PMID: 24596416). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CART123 cells | CART123 cells | 0 | 2 |
| CART123 cells + Ruxolitinib | CART123 cells Ruxolitinib | 0 | 1 |
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