Ruxolitinib
Drug Detail
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| Drug Name | Ruxolitinib |
| Trade Name | Jakafi |
| Synonyms | INCB 18424|INCB018424|INCB18424 |
| Drug Descriptions |
Jakafi (ruxolitinib) is an inhibitor of protein tyrosine kinases JAK1 and JAK2, thus resulting in reduced inflammation and reduced proliferation (PMID: 22474318). Jakafi (ruxolitinib) is FDA approved to treat bone marrow cancer, specifically intermediate or high-risk myelofibrosis (FDA.gov) |
| DrugClasses | JAK1 Inhibitor - ATP competitive 5 JAK2 Inhibitor - ATP competitive 15 |
| CAS Registry Number | 941678-49-5 |
| NCIT ID | C77888 |
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