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Drug Name | HuCART-meso cells |
Trade Name | |
Synonyms | anti-MSLN CAR-T Cells |
Drug Descriptions |
HuCART-meso cells are T-lymphocytes that have been engineered to express a chimeric antigen receptor (CAR) that targets mesothelin and contains the zeta chain of CD3 (CD3zeta) and other costimulatory domains, which potentially leads to increased antitumor immune response (PMID: 26973126, PMID: 31420241). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C155909 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
HuCART-meso cells | HuCART-meso cells | 0 | 3 |
HuCART-meso cells + VCN-01 | HuCART-meso cells VCN-01 | 0 | 1 |