Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Therapy Name | HuCART-meso cells |
Synonyms | |
Therapy Description |
HuCART-meso cells are T-lymphocytes that have been engineered to express a chimeric antigen receptor (CAR) that targets mesothelin and contains the zeta chain of CD3 (CD3zeta) and other costimulatory domains, which potentially leads to increased antitumor immune response (PMID: 26973126, PMID: 31420241). |