NUC-3373
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| Drug Name | NUC-3373 |
| Trade Name | |
| Synonyms | NUC 3373|NUC3373|fosifloxuridine nafalbenamide |
| Drug Descriptions |
NUC-3373 is a fluoropyrimidine that is incorpororated into DNA and inhibits thymidylate synthetase, potentially leading to induction of DNA damage and cell cycle arrest (PMID: 37000221). |
| DrugClasses | |
| CAS Registry Number | 1332837-31-6 |
| NCIT ID | C156680 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Docetaxel + Leucovorin + NUC-3373 | Docetaxel Leucovorin NUC-3373 | 0 | 1 |
| Leucovorin + NUC-3373 + Pembrolizumab | Leucovorin NUC-3373 Pembrolizumab | 0 | 1 |
| NUC-3373 | NUC-3373 | 0 | 0 |
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