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Drug Name NUC-3373
Trade Name
Synonyms NUC 3373|NUC3373|fosifloxuridine nafalbenamide
Drug Descriptions

NUC-3373 is a fluoropyrimidine that is incorpororated into DNA and inhibits thymidylate synthetase, potentially leading to induction of DNA damage and cell cycle arrest (PMID: 37000221).

DrugClasses
CAS Registry Number 1332837-31-6
NCIT ID C156680

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Docetaxel + Leucovorin + NUC-3373 Docetaxel Leucovorin NUC-3373 0 1
Leucovorin + NUC-3373 + Pembrolizumab Leucovorin NUC-3373 Pembrolizumab 0 1
NUC-3373 NUC-3373 0 0


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