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| Drug Name | TC-510 |
| Trade Name | |
| Synonyms | TC 510|TC510 |
| Drug Descriptions |
TC-510 are autologous T-lymphocytes engineered to express both an anti-mesothelin (MSLN) antibody fused to the N-terminus of the CD3-epsilon subunit of the T-cell receptor complex as well as a PD-1:CD28 switch receptor, which potentially induce activation of T-lymphocytes, decrease PD-1/PD-L1 pathway-dependent T-cell suppression, and induce killing of tumor cells expressing MSLN (NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C188805 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| TC-510 | TC-510 | 0 | 1 |
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