BYON4228
Drug Detail
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| Drug Name | BYON4228 |
| Trade Name | |
| Synonyms | BYON-4228|BYON 4228 |
| Drug Descriptions |
BYON4228 is a monoclonal antibody that targets SIRPA, including polymorphic variants of SIRPA, and prevents its interaction with CD47, which potentially enhances macrophage and neutrophil-dependent tumor cell killing (PMID: 37068796). |
| DrugClasses | SIRPA Antibody 7 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BYON4228 | BYON4228 | 0 | 0 |
| BYON4228 + Pembrolizumab | BYON4228 Pembrolizumab | 0 | 1 |
| BYON4228 + Rituximab | BYON4228 Rituximab | 0 | 1 |
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