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Drug Name AB598
Trade Name
Synonyms AB 598|AB-598
Drug Descriptions

AB598 is an inhibitory monoclonal antibody against ENTPD1 (CD39), which blocks ATPase activity, leading to increased extracellular ATP and potential activation of the tumor microenvironment and inhibition of tumor growth (PMID: 38797955).

DrugClasses CD39 Antibody 5
CAS Registry Number NA
NCIT ID C200795

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB598 AB598 0 1
AB598 + Carboplatin + Pemetrexed Disodium + Zimberelimab AB598 Carboplatin Pemetrexed Disodium Zimberelimab 0 1
AB598 + Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab AB598 Fluorouracil Leucovorin Oxaliplatin Zimberelimab 0 1


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