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Drug Name Zimberelimab
Trade Name
Synonyms GLS-010|AB122|AB-122|GLS010
Drug Descriptions

Zimberelimab (GLS-010) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 28679395).

DrugClasses Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121
CAS Registry Number 2259860-24-5
NCIT ID C159549

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB154 + AB680 + Zimberelimab AB154 AB680 Zimberelimab 0 1
AB154 + Capecitabine + Oxaliplatin + Zimberelimab AB154 Capecitabine Oxaliplatin Zimberelimab 0 1
AB154 + Carboplatin + Nab-paclitaxel + Zimberelimab AB154 Carboplatin Nab-paclitaxel Zimberelimab 0 1
AB154 + Carboplatin + Paclitaxel + Zimberelimab AB154 Carboplatin Paclitaxel Zimberelimab 0 1
AB154 + Carboplatin + Pemetrexed Disodium + Zimberelimab AB154 Carboplatin Pemetrexed Disodium Zimberelimab 0 1
AB154 + Cisplatin + Pemetrexed Disodium + Zimberelimab AB154 Cisplatin Pemetrexed Disodium Zimberelimab 0 1
AB154 + Docetaxel + Zimberelimab AB154 Docetaxel Zimberelimab 0 1
AB154 + Etrumadenant + Zimberelimab AB154 Etrumadenant Zimberelimab 0 3
AB154 + Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab AB154 Fluorouracil Leucovorin Oxaliplatin Zimberelimab 0 2
AB154 + Sacituzumab govitecan-hziy + Zimberelimab AB154 Sacituzumab govitecan-hziy Zimberelimab 0 2
AB154 + Sotigalimab + Zimberelimab AB154 Sotigalimab Zimberelimab 0 1
AB154 + Zimberelimab AB154 Zimberelimab 0 8
AB308 + Zimberelimab AB308 Zimberelimab 0 1
AB598 + Carboplatin + Pemetrexed Disodium + Zimberelimab AB598 Carboplatin Pemetrexed Disodium Zimberelimab 0 1
AB598 + Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab AB598 Fluorouracil Leucovorin Oxaliplatin Zimberelimab 0 1
AB680 + Cisplatin + Gemcitabine + Zimberelimab AB680 Cisplatin Gemcitabine Zimberelimab 0 1
AB680 + Docetaxel + Zimberelimab AB680 Docetaxel Zimberelimab 0 1
AB680 + Etrumadenant + Zimberelimab AB680 Etrumadenant Zimberelimab 0 4
AB680 + Gemcitabine + Nab-paclitaxel + Zimberelimab AB680 Gemcitabine Nab-paclitaxel Zimberelimab 0 0
AB680 + Irinotecan + Leucovorin + Oxaliplatin + Zimberelimab AB680 Irinotecan Leucovorin Oxaliplatin Zimberelimab 0 1
AB680 + Zimberelimab AB680 Zimberelimab 0 4
AB801 + Docetaxel + Zimberelimab AB801 Docetaxel Zimberelimab 0 1
Bevacizumab + Etrumadenant + Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab Bevacizumab Etrumadenant Fluorouracil Leucovorin Oxaliplatin Zimberelimab 0 1
Carboplatin + Nab-paclitaxel + Zimberelimab Carboplatin Nab-paclitaxel Zimberelimab 0 1
Carboplatin + Paclitaxel + Zimberelimab Carboplatin Paclitaxel Zimberelimab 0 1
Carboplatin + Pemetrexed Disodium + Zimberelimab Carboplatin Pemetrexed Disodium Zimberelimab 0 1
Cisplatin + Etrumadenant + Zimberelimab Cisplatin Etrumadenant Zimberelimab 0 1
Cisplatin + Pemetrexed Disodium + Zimberelimab Cisplatin Pemetrexed Disodium Zimberelimab 0 1
Cisplatin + Zimberelimab Cisplatin Zimberelimab 0 1
Docetaxel + Etrumadenant + Zimberelimab Docetaxel Etrumadenant Zimberelimab 0 1
Enzalutamide + Etrumadenant + Zimberelimab Enzalutamide Etrumadenant Zimberelimab 0 1
Etrumadenant + Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab Etrumadenant Fluorouracil Leucovorin Oxaliplatin Zimberelimab 0 2
Etrumadenant + Pemetrexed Disodium + Zimberelimab Etrumadenant Pemetrexed Disodium Zimberelimab 0 1
Etrumadenant + Sacituzumab govitecan-hziy + Zimberelimab Etrumadenant Sacituzumab govitecan-hziy Zimberelimab 0 1
Etrumadenant + SRF617 + Zimberelimab Etrumadenant SRF617 Zimberelimab 0 1
Etrumadenant + Zimberelimab Etrumadenant Zimberelimab 0 4
Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab Fluorouracil Leucovorin Oxaliplatin Zimberelimab 0 1
GS-2121 + Zimberelimab GS-2121 Zimberelimab 0 1
GS-4528 + Zimberelimab GS-4528 Zimberelimab 0 1
GS-9911 + Zimberelimab GS-9911 Zimberelimab 0 1
Sacituzumab govitecan-hziy + Zimberelimab Sacituzumab govitecan-hziy Zimberelimab 0 3
Zimberelimab Zimberelimab 0 8


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