A2B694
Drug Detail
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| Drug Name | A2B694 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
A2B694 are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting MSLN, an LIR-1-based inhibitory receptor targeting HLA-A*02, and an shRNA targeting beta2 microglobulin, which may induce tumor killing and inhibit tumor growth (Journal for ImmunoTherapy of Cancer 2022;10). |
| DrugClasses | MSLN Immune Cell Therapy 10 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| A2B694 | A2B694 | 0 | 1 |
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