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Drug Name | SAR445514 |
Trade Name | |
Synonyms | SAR 445514|SAR-445514|IPH 6401|IPH-6401|IPH6401|SAR514|SAR'514 |
Drug Descriptions |
SAR445514 is a trifunctional natural killer (NK) cell engager (NKCE) that binds to NKp46 and CD16a on NK cells leading to activation and redirects NK cells towards TNFRSF17 (BCMA)-expressing tumor cells, potentially resulting in increased tumor cell killing (Cancer Res (2023) 83 (7_Supplement): 2960). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C200560 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
SAR445514 | SAR445514 | 0 | 1 |