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Therapy Name | SAR445514 |
Synonyms | |
Therapy Description |
SAR445514 is a trifunctional natural killer (NK) cell engager (NKCE) that binds to NKp46 and CD16a on NK cells leading to activation and redirects NK cells towards TNFRSF17 (BCMA)-expressing tumor cells, potentially resulting in increased tumor cell killing (Cancer Res (2023) 83 (7_Supplement): 2960). |