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Drug Name | KGX101 |
Trade Name | |
Synonyms | KGX-101|KGX 101 |
Drug Descriptions |
KGX101 is a prodrug comprising IL12 linked to an IL12RB-derived masking domain via a protease-sensitive linker that is cleaved by proteases in the tumor microenvironment, activating IL12 signaling and potentially stimulating an immune response and inhibiting tumor growth (Cancer Res (2024) 84 (6_Supplement): 4068). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C202246 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
KGX101 | KGX101 | 0 | 1 |
KGX101 + unspecified PD-L1 antibody | KGX101 unspecified PD-L1 antibody | 0 | 0 |