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Drug Name | AZD5851 |
Trade Name | |
Synonyms | AZD-5851|AZD 5851|Autologous dnTGF-BRII-armored Anti-GPC3 CAR T-cells |
Drug Descriptions |
AZD5851 comprises T-cells engineered to express a chimeric antigen receptor (CAR) targeting GPC3 and a dominant negative TGF-beta type II receptor, which may inhibit tumor growth (J Immunol (2023) 210 (1_Supplement): 68.17) |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C202234 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZD5851 | AZD5851 | 0 | 1 |