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Drug Name | TGRX-678 |
Trade Name | |
Synonyms | TGRX 678|TGRX678 |
Drug Descriptions |
TGRX-678 inhibits BCR-ABL1 and ABL1 mutations including T315I, potentially resulting in decreased cell proliferation and inhibition of tumor growth (Blood (2023) 142 (Supplement 1): 2807). |
DrugClasses | ABL1 Inhibitor 8 BCR-ABL Inhibitor 32 |
CAS Registry Number | NA |
NCIT ID | C202237 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Ponatinib + TGRX-678 | Ponatinib TGRX-678 | 0 | 0 |
TGRX-678 | TGRX-678 | 0 | 1 |