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Drug Name TGRX-678
Trade Name
Synonyms TGRX 678|TGRX678
Drug Descriptions

TGRX-678 inhibits BCR-ABL1 and ABL1 mutations including T315I, potentially resulting in decreased cell proliferation and inhibition of tumor growth (Blood (2023) 142 (Supplement 1): 2807).

DrugClasses ABL1 Inhibitor 8 BCR-ABL Inhibitor 32
CAS Registry Number NA
NCIT ID C202237

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ponatinib + TGRX-678 Ponatinib TGRX-678 0 0
TGRX-678 TGRX-678 0 1


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