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Therapy Name TGRX-678
Synonyms
Therapy Description

TGRX-678 inhibits BCR-ABL1 and ABL1 mutations including T315I, potentially resulting in decreased cell proliferation and inhibition of tumor growth (Blood (2023) 142 (Supplement 1): 2807).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
TGRX-678 TGRX 678|TGRX678 ABL1 Inhibitor 8 BCR-ABL Inhibitor 32 TGRX-678 inhibits BCR-ABL1 and ABL1 mutations including T315I, potentially resulting in decreased cell proliferation and inhibition of tumor growth (Blood (2023) 142 (Supplement 1): 2807).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06088888 Phase I TGRX-678 TGRX-678 US Phase I for Subjects With Refractory or Advanced Chronic Myelogenous Leukemia Recruiting USA 0


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