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Drug Name | BI 3706674 |
Trade Name | |
Synonyms | BI-3706674|BI3706674 |
Drug Descriptions |
BI 3706674 is a selective KRAS inhibitor, which non-covalently binds KRAS wild-type and mutant alleles, including G12A/C/D/V, G13D, and Q61H, potentially inhibiting Kras signaling and tumor growth (Cancer Res (2024) 84 (6_Supplement): 3317). |
DrugClasses | KRAS Inhibitor 18 |
CAS Registry Number | NA |
NCIT ID | C202247 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BI 1701963 + BI 3706674 | BI 1701963 BI 3706674 | 0 | 0 |
BI 3706674 | BI 3706674 | 0 | 1 |
BI 3706674 + Cetuximab | BI 3706674 Cetuximab | 0 | 0 |