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Drug Name RO7496353
Trade Name
Synonyms RO-7496353|RO 7496353|SOF 10|SOF10|SOF-10|RG 6440|RG 6440|RG6440
Drug Descriptions

RO7496353 is a monoclonal antibody targeting TGFb1, which potentially induces increased antitumor immune response, decreased tumor cell proliferation, and cytotoxicity against tumor cells (NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C200803

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Gemcitabine + Nab-paclitaxel + RO7496353 Atezolizumab Gemcitabine Nab-paclitaxel RO7496353 0 1
Atezolizumab + RO7496353 Atezolizumab RO7496353 0 1
Capecitabine + Nivolumab + Oxaliplatin + RO7496353 Capecitabine Nivolumab Oxaliplatin RO7496353 0 1
Nivolumab + Oxaliplatin + RO7496353 + Tegafur-gimeracil-oteracil Potassium Nivolumab Oxaliplatin RO7496353 Tegafur-gimeracil-oteracil Potassium 0 1
RO7496353 RO7496353 0 0


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