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| Drug Name | PYX-201 |
| Trade Name | |
| Synonyms | PYX201|PYX 201 |
| Drug Descriptions |
PYX-201 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting the extra domain B (EDB) splice variant of fibronectin linked to Aur0101, which delivers the cytotoxic agent to tumor cells, potentially inducing tumor cell killing and inhibition of tumor growth (PMID: 36876967). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C200116 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Pembrolizumab + PYX-201 | PYX-201 Pembrolizumab | 0 | 1 |
| PYX-201 | PYX-201 | 0 | 1 |