NT-112
Drug Detail
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| Drug Name | NT-112 |
| Trade Name | |
| Synonyms | NT112|NT 112 |
| Drug Descriptions |
NT-112 comprises autologous T lymphocytes engineered to express an HLA-C*08:02-restricted T-cell receptor (TCR) targeting KRAS G12D, which potentially induces cytotoxic T-lymphocyte (CTL)-dependent killing of tumor cells expressing KRAS G12D and inhibits tumor growth (Clin Oncol 42, 2024 (suppl 16; e14533, NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C204099 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| NT-112 | NT-112 | 0 | 1 |
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