TmPSMA-02 CAR-T cells
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| Drug Name | TmPSMA-02 CAR-T cells |
| Trade Name | |
| Synonyms | TmPSMA 02|TmPSMA-02 |
| Drug Descriptions |
TmPSMA-02 CAR-T cells are autologous T-lymphocytes engineered to express a CD2 endodomain-containing chimeric antigen receptor (CAR) targeting PSMA, a dominant negative form of TGFBR2, and a PD-1-CD28 switch receptor, which may induce toxicity against PSMA-expressing tumor cells (J Clin Oncol 40, no. 6_suppl (February 16, 2022) 158, NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C190115 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| TmPSMA-02 CAR-T cells | TmPSMA-02 CAR-T cells | 0 | 1 |
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