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| Drug Name | AttIL12 T-cells |
| Trade Name | |
| Synonyms | AttIL12 armed T cells|attIL12-expressing T-cells |
| Drug Descriptions |
AttIL12 T-cells are T-lymphocytes engineered to express membrane-anchored IL12 targeted to cell-surface vimentin (CSV), which potentially induce cytotoxicity in CSV-expressing tumor cells, enhance antitumor immune response, and inhibit tumor growth (PMID: 35027427). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C190860 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AttIL12 T-cells | AttIL12 T-cells | 0 | 1 |
| AttIL12 T-cells + Cyclophosphamide | AttIL12 T-cells Cyclophosphamide | 0 | 1 |
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