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Therapy Name | AttIL12 T-cells |
Synonyms | |
Therapy Description |
AttIL12 T-cells are T-lymphocytes engineered to express membrane-anchored IL12 targeted to cell-surface vimentin (CSV), which potentially induce cytotoxicity in CSV-expressing tumor cells, enhance antitumor immune response, and inhibit tumor growth (PMID: 35027427). |