Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Autologous CXCR2-modified CD70 CAR-T cells |
Trade Name | |
Synonyms | autologous 8R-70CAR T-cells|autologous IL-8RB-modified CD70-CAR T-cells |
Drug Descriptions |
Autologous CXCR2-modified CD70 CAR-T cells are autologous T-lymphocytes engineered to express the IL-8 receptor CXCR2 and a chimeric antigen receptor (CAR) targeting CD70, which may increase antitumor immune response and inhibit tumor growth (PMID: 31488817). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C187688 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Autologous CXCR2-modified CD70 CAR-T cells | Autologous CXCR2-modified CD70 CAR-T cells | 0 | 1 |