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Drug Name | DM919 |
Trade Name | |
Synonyms | |
Drug Descriptions |
DM919 is a monoclonal antibody that binds to membrane and soluble MICA/B, resulting in increased cell surface expression and decreased serum MICA/B levels, which potentially leads to increased NKG2D-dependent activation of NK cells and tumor growth inhibition (Journal for ImmunoTherapy of Cancer 2023;11:1355). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
DM919 | DM919 | 0 | 1 |
DM919 + Pembrolizumab | DM919 Pembrolizumab | 0 | 1 |