OBI-992
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| Drug Name | OBI-992 |
| Trade Name | |
| Synonyms | OBI992|OBI 992|BSI 992|BSI-992|BSI992 |
| Drug Descriptions |
OBI-992 is an antibody-drug conjugate (ADC) comprising an antibody targeting TACSTD2 (TROP2) linked to a topoisomerase I inhibitor, which may induce cytotoxicity against TROP2-expressing tumor cells and inhibit tumor growth (PMID: 39786401). |
| DrugClasses | TROP2 Antibody 18 |
| CAS Registry Number | NA |
| NCIT ID | C207806 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| OBI-992 | OBI-992 | 0 | 1 |
| OBI-992 + Olaparib | OBI-992 Olaparib | 0 | 0 |
| OBI-992 + Talazoparib | OBI-992 Talazoparib | 0 | 0 |
| OBI-992 + unspecified PD-1 antibody | OBI-992 unspecified PD-1 antibody | 0 | 0 |
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