Therapy Detail
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| Therapy Name | OBI-992 |
| Synonyms | |
| Therapy Description |
OBI-992 is an antibody-drug conjugate (ADC) comprising an antibody targeting TACSTD2 (TROP2) linked to a topoisomerase I inhibitor, which may induce cytotoxicity against TROP2-expressing tumor cells and inhibit tumor growth (PMID: 39786401). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| OBI-992 | OBI992|OBI 992|BSI 992|BSI-992|BSI992 | TROP2 Antibody 18 | OBI-992 is an antibody-drug conjugate (ADC) comprising an antibody targeting TACSTD2 (TROP2) linked to a topoisomerase I inhibitor, which may induce cytotoxicity against TROP2-expressing tumor cells and inhibit tumor growth (PMID: 39786401). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06480240 | Phase Ib/II | OBI-992 | A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors | Active, not recruiting | USA | 1 |
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