Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | KQB198 |
| Trade Name | |
| Synonyms | KQB-198|KQB 198 |
| Drug Descriptions |
KQB198 inhibits SOS1, potentially leading to decreased downstream KRAS signaling and reduced growth of tumor cells expressing KRAS (NCI Drug Dictionary). |
| DrugClasses | SOS1 Inhibitor 17 |
| CAS Registry Number | NA |
| NCIT ID | C211867 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Dasatinib + KQB198 | Dasatinib KQB198 | 0 | 1 |
| KQB198 | KQB198 | 0 | 2 |
| KQB198 + Osimertinib | KQB198 Osimertinib | 0 | 1 |